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Results for "

Tau Protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Tau Protein (15) Amyloid-β (10) Apoptosis (3) Bacterial (1) Caspase (1) CDK (2) Cholinesterase (ChE) (4) Dengue virus (1) Dopamine Receptor (1) DYRK (1) Flavivirus (1) Fungal (1) GSK-3 (7) HDAC (1) Histamine Receptor (1) Ligands for E3 Ligase (1) Microtubule/Tubulin (6) Phosphatase (3) PROTACs (1) Reactive Oxygen Species (1) α-synuclein (1)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (2) Neurological Disease (34)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: Tau Protein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1707A

Tau protein (592-597), human TFA	Tau Protein	Neurological Disease
Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia .

HY-153427

Tau protein aggregation-IN-1	Tau Protein	Neurological Disease
Tau protein aggregation-IN-1 (Compound 0c) is a **Tau protein** aggregation inhibitor. Tau protein aggregation-IN-1 can be used in the study of protein folding disorders such as Alzheimer's disease, dementia, Parkinson's disease, Huntington's disease and prion-based spongiform encephalopathies .

HY-156435

tau protein/α-synuclein-IN-1	α-synuclein	Neurological Disease
tau protein/α-synuclein-IN-1 is a dual inhibitor of **tau protein and α-synuclein*. tau* protein/α-synuclein-IN-1 reduces α-syn inclusions development in M17D neuroblastoma cells. tau protein/α-synuclein-IN-1 can be used in study Alzheimer’s disease .

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P4808

PHF6	Amyloid-β	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-138643

Cl-NQTrp

Amyloid-β Neurological Disease

Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein .

Cl-NQTrp	Amyloid-β	Neurological Disease
Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein .

HY-P0181

*Microtubule-associated protein* tau (26-44)**	Tau Protein	Neurological Disease
Microtubule-associated protein tau (26-44) is a synthetic peptide chain with an amine group attached to glutamine and an carboxyl group attached to lysine.

HY-P9995

Posdinemab

JNJ-63733657
Tau Protein Cancer

Posdinemab is a humanized IgG1κ antibody, targeting to microtubule-associated protein tau (MAPT) .

Posdinemab JNJ-63733657	Tau Protein	Cancer
Posdinemab is a humanized IgG1κ antibody, targeting to microtubule-associated protein tau (MAPT) .

HY-155366

hAChE-IN-6	Cholinesterase (ChE) GSK-3	Neurological Disease
hAChE-IN-6 (compound 51) is a brain penetrant AChE inhibitor with an IC₅₀ of 0.16 μM. hAChE-IN-6 also inhibits hBuChE and GSK3β with IC₅₀ values of 0.69 μM and 0.26 μM, respectively. hAChE-IN-6 inhibits tau protein and Aβ1-42 self-aggregation, and can be used for Alzheimer's disease (AD) research .

HY-134879

Tau tracer 1	Microtubule/Tubulin	Neurological Disease
Tau tracer 1 is a Tau tracer used for imaging Tau protein aggregates. Tau tracer 1 can be used to diagnose neurodegenerative diseases .

HY-134880

Tau tracer 2 Pl-2620	Microtubule/Tubulin	Neurological Disease
Tau tracer 2 (Pl-2620) is a Tau tracer used for imaging Tau protein aggregates. Tau tracer 2 can be used to diagnose neurodegenerative diseases .

HY-13486

TAU-IN-1	Tau Protein	Neurological Disease
TAU-IN-1 (compound 051) is a *TAU* protein inhibitor with an EC₅₀ value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases .

HY-155365

hAChE-IN-5	Cholinesterase (ChE) GSK-3 Amyloid-β	Neurological Disease
hAChE-IN-5 (compound 49) is a potent hAChE and hBuChE inhibitor with IC₅₀ values of 0.17 μM and 0.17 μM, respectively. hAChE-IN-5 shows potent GSK3β inhibition with an IC₅₀ value of 0.21 μM. hAChE-IN-5 is used as *tau* protein aggregation and Aβ1-42 self-aggregation inhibitor. hAChE-IN-5 can bind virtually with the PAS affecting Aβ aggregation, thus preventing Aβ-dependent neurotoxicity. hAChE-IN-5 can penetrate BBB and has the potential for multi-targeted anti-Alzheimer's agents research .

HY-146135

Tau-aggregation-IN-1	Microtubule/Tubulin Dopamine Receptor	Neurological Disease
Tau-aggregation-IN-1 (Compound D-519) is a *tau441* protein aggregation inhibitor with an IC₅₀ of 21 µM. Tau-aggregation-IN-1 is also a dopamine D₂ and D₃ receptor agonist .

HY-101181

THK-5105	Microtubule/Tubulin	Neurological Disease
THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe .

HY-P99399

Semorinemab RG 6100; RO7105705; MTau-9937A	Tau Protein	Neurological Disease
Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a K_d value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease .

HY-101182

THK-5117	Microtubule/Tubulin	Neurological Disease
THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a K_i of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe .

HY-P99163

Tilavonemab ABBV-8E12; C2N-8E12	Microtubule/Tubulin	Neurological Disease
Tilavonemab (ABBV-8E12) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the *tau* protein. Tilavonemab blocks the ability of human and mouse neurons to take up *tau* aggregates and reduces brain atrophy. Tilavonemab can be used in the study of Alzheimer's disease .

HY-138669

C004019	PROTACs Tau Protein	Neurological Disease
C004019 is a small-molecule PROTAC. C004019 simultaneously recruites *tau* and E3-ligase (Vhl) and thus selectively enhances ubiquitination and proteolysis of *tau* proteins. C004019 can be used for Alzheimer disease (AD) research .

HY-153430

Aβ/tau aggregation-IN-3	Amyloid-β	Neurological Disease
Aβ/tau aggregation-IN-3 is a potent *amyloid protein* aggregation inhibitor with an IC₅₀** of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. Aβ/tau aggregation-IN-3 has anti-amyloid activity .

HY-P4822

Acetyl-PHF5 amide

Tau Protein Others

Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .
HY-144290

ARN25068

GSK-3 DYRK Neurological Disease

ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .

Acetyl-PHF5 amide	Tau Protein	Others
Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .

ARN25068	GSK-3 DYRK	Neurological Disease
ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .

HY-N3225

Myricanol	Others	Others
Myricanol is a constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark. Myricanol can lower the levels of the microtubule-associated protein tau (MAPT) .

HY-D1443

BSB (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene	Amyloid-β	Others
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .

HY-19738

NQTrp
NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the **tau protein** with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide ( ⁴¹GCWMLY ⁴⁶ within the N-terminus of γD-crystallin) as well as full-length γD-crystallin .

HY-158030

HDAC6-IN-37	HDAC	Neurological Disease
HDAC6-IN-37 (compound W5) is an inhibitor of HDAC6 and has neuroprotective effects. HDAC6-IN-37 can restore the morphology of hippocampal neurons, reduce the expression of Aβ, Tau, and p-Tau proteins in the hippocampus of AD rats, and inhibit the formation of senile plaques and neurofibrillary tangles. Thus, HDAC6-IN-37 improves the Aβ/Cu ²⁺-induced AD model in rats, regulates oxidative stress status, and balances neurotransmitter disorders in brain tissue .

HY-19948

Leucomethylene blue mesylate 5 Publications Verification TRx0237 mesylate; Methylene blue leuco base mesylate	Amyloid-β	Neurological Disease
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation *tau* protein aggregation inhibitor (K_i of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes .

HY-P4933

Tau Peptide (255-314) (Repeat 2 Domain) (human)	Tau Protein	Others
Tau Peptide (255-314) (Repeat 2 Domain) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-N3187

Nimbin	Flavivirus Dengue virus Fungal Bacterial Histamine Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents *tau* aggregation and increases cell viability. Nimbin is effective inhibits the *envelope protein* of dengue virus**. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier .

HY-132927A

Salpyran hydrochloride

Others Others

Salpyran is a Cu(II) selective chelator with therapeutic potential .

Salpyran hydrochloride	Others	Others
Salpyran is a Cu(II) selective chelator with therapeutic potential .

HY-132927B

Salpyran dihydrochloride	Reactive Oxygen Species	Inflammation/Immunology
Salpyran dihydrochloride is a Cu(II) selective chelator with therapeutic potential. Salpyran dihydrochloride prevents the formation of reactive oxygen species from the binary Cu(II)/H₂O₂ system .

HY-124832

δ-Secretase inhibitor 11	Caspase Amyloid-β	Neurological Disease
δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC₅₀ of 0.7 μM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research .

HY-150585

BuChE-IN-5	Amyloid-β Cholinesterase (ChE) Tau Protein	Neurological Disease
BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC₅₀ value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and **tau protein** in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease .

HY-149273

hBChE-IN-1	Cholinesterase (ChE) Amyloid-β Tau Protein	Neurological Disease
hBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC₅₀=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against *tau* and Aβ₄₀ protein aggregation, with IC₅₀ values of 20 and 4.3 μM, respectively. hBChE-IN-1 can be used for Alzheimer's disease research .

HY-138678

(R,S,S)-VH032	Ligands for E3 Ligase	Cancer
(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669) .

HY-116753

(-)Clausenamide	Amyloid-β Tau Protein	Neurological Disease
(-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of *tau* protein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ_25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD) .

HY-N6785

Okadaic acid Maximum Cited Publications 7 Publications Verification	Phosphatase Apoptosis	Neurological Disease Cancer
Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC₅₀=0.1-0.3 nM), and inhibits PP1 (IC₅₀=15-50 nM), PP3 (IC₅₀=3.7-4 nM), PP4 (IC₅₀=0.1 nM), PP5 (IC₅₀=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation .

HY-N6785A

Okadaic acid sodium	Phosphatase Apoptosis	Neurological Disease Cancer
Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A (IC₅₀=0.1-0.3 nM), and inhibits PP1 (IC₅₀=15-50 nM), PP3 (IC₅₀=3.7-4 nM), PP4 (IC₅₀=0.1 nM), PP5 (IC₅₀=3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation .

HY-122026

PF-04802367 PF-367	GSK-3	Neurological Disease
PF-04802367 (PF-367) is a highly selective GSK-3 inhibitor with an IC₅₀ of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. PF-04802367 shows desirable central nervous system (CNS) properties and potency. PF-04802367 is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3α and GSK-3β) with IC₅₀ values of 10.0 and 9.0 nM in mobility shift assays, respectively .

HY-115760

Okadaic acid ammonium salt	Phosphatase	Neurological Disease Cancer
Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC₅₀=0.1-0.3 nM), and inhibits PP1 (IC₅₀=15-50 nM), PP3 (IC₅₀=3.7-4 nM), PP4 (IC₅₀=0.1 nM), PP5 (IC₅₀=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation .

HY-154852

GSK-3 inhibitor 4	GSK-3 CDK	Neurological Disease
GSK-3 inhibitor 4 is an orally active and brain-penetrant inhibitor of GSK-3, CDK2, and CDK5, with IC₅₀ values of 0.56 nM (GSK-3β), 0.45 nM (GSK-3α), 0.47 μM, and 0.68 μM, respectively. GSK-3 inhibitor 4 effectively reduces the phosphorylation level of **Tau protein**. GSK-3 inhibitor 4 can be used in Alzheimer's disease (AD) studies .

HY-154851

GSK-3 inhibitor 3	GSK-3 CDK Tau Protein	Neurological Disease
GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC₅₀s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. GSK-3 inhibitor 3 lowers levels of **tau protein phosphorylation at S396 in a triple-transgenic mouse Alzheimer’s disease model, with IC₅₀** of 10 nM. GSK-3 inhibitor 3 can be used for neurological disease research .

HY-149542

GSK-3β inhibitor 15	Tau Protein Apoptosis GSK-3	Neurological Disease
GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC₅₀: 3.4 nM). GSK-3β inhibitor 15 inhibits Aβ_1-42-induced GSK-3β and **tau protein** phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ_1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD) .

Leucomethylene blue mesylate 5 Publications Verification TRx0237 mesylate; Methylene blue leuco base mesylate	Chromogenic Assays
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation *tau* protein aggregation inhibitor (K_i of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes .

Cat. No.	Product Name	Target	Research Area

HY-P1707A

Tau protein (592-597), human TFA	Tau Protein	Neurological Disease
Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia .

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P4808

PHF6	Amyloid-β	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P0181

*Microtubule-associated protein* tau (26-44)**	Tau Protein	Neurological Disease
Microtubule-associated protein tau (26-44) is a synthetic peptide chain with an amine group attached to glutamine and an carboxyl group attached to lysine.

HY-P4822

Acetyl-PHF5 amide

Tau Protein Others

Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .

HY-P4691

(Ser(PO3H2)396,404)-Tau Peptide (379-408)	Peptides	Others
(Ser(PO3H2)396,404)-Tau Peptide (379-408) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4686

(Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213)	Peptides	Others
(Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4935

Tau Peptide (268-282)	Peptides	Others
Tau Peptide (268-282) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4949

Tau Peptide (274-288)	Peptides	Others
Tau Peptide (274-288) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4959

Tau Peptide (277-291)	Peptides	Others
Tau Peptide (277-291) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4961

Tau Peptide (295-309)	Peptides	Others
Tau Peptide (295-309) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4962

Tau Peptide (298-312)	Peptides	Others
Tau Peptide (298-312) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4963

Tau Peptide (301-315)	Peptides	Others
Tau Peptide (301-315) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4964

Tau Peptide (304-318)	Peptides	Others
Tau Peptide (304-318) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4965

Tau Peptide (306-317)	Peptides	Others
Tau Peptide (306-317) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4967

Tau Peptide (307-321)	Peptides	Others
Tau Peptide (307-321) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4974

Tau Peptide (512-525) amide	Peptides	Others
Tau Peptide (512-525) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4968

Tau Peptide (337-368) (Repeat 4 Domain)	Peptides	Others
Tau Peptide (337-368) (Repeat 4 Domain) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4830

Acetyl-Tau Peptide (244-274) (Repeat 1 Domain)	Peptides	Others
Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4933

Tau Peptide (255-314) (Repeat 2 Domain) (human)	Tau Protein	Others
Tau Peptide (255-314) (Repeat 2 Domain) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Species:	Human (8) Rhesus Macaque (1) Mouse (2) Rat (2) Bovine (1)
Tag:	His (11) Tag Free (1) GST (4) Flag (2)
Source:	HEK293 (4) Sf9 insect cells (3) P. pastoris (3) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P701658

	*CK1d Protein, Human (Sf9, GST)* CSNK1D; Casein kinase I isoform delta; CKI-delta; CKId; Tau-Protein kinase CSNK1D	Human	Sf9 insect cells
	The CK1d protein is an important serine/threonine protein kinase that complexly controls cellular processes such as Wnt signaling, DNA repair, and circadian rhythms. Its versatility is evident in phosphorylating a variety of proteins, including connexin-43/GJA1, MAP1A, p53/TP53, and YAP1. CK1d Protein, Human (Sf9, GST) is the recombinant human-derived CK1d protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CK1d Protein, Human (Sf9, GST) is 414 a.a., .

HY-P702685

	*CDK5-p25 Protein, Human (sf9, GST, His, Flag)* CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; Protein kinase CDK5 splicing; cell division Protein kinase 5; serine/threonine-Protein kinase PSSALRE; Tau Protein kinase II catalytic subunit	Human	Sf9 insect cells

HY-P702686

	*CDK5-p35 Protein, Human (sf9, GST, His, Flag)* CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; Protein kinase CDK5 splicing; cell division Protein kinase 5; serine/threonine-Protein kinase PSSALRE; Tau Protein kinase II catalytic subunit	Human	Sf9 insect cells

HY-P71752

	*Microtubule-associated protein* tau Protein, Mouse (P.pastoris, His)** Mapt; Mtapt; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	Mouse	P. pastoris
	Microtubule-associated protein tau (MAPT) plays a key role in promoting microtubule assembly and stability, suggesting its potential contribution to the establishment of neuronal polarity. The C terminus binds to axonal microtubules, whereas the N terminus interacts with neuroplasmic membrane components, serving as a key linker protein between these structures. Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Microtubule-associated protein tau protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is 732 a.a., with molecular weight of ~78.1 kDa.

HY-P71753

	*Microtubule-associated protein* tau Protein, Rat (P.pastoris, His)** Mapt; Mtapt; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	Rat	P. pastoris
	Microtubule-associated protein tau (MAPT) critically promotes microtubule assembly and stability, influencing neuronal polarity by acting as an important junction protein. Its dual role involves C-terminal binding to axonal microtubules and N-terminal binding to neuroplasmic membrane components. Microtubule-associated protein tau Protein, Rat (P.pastoris, His) is the recombinant rat-derived Microtubule-associated protein tau protein, expressed by P. pastoris , with N-His labeled tag. The total length of Microtubule-associated protein tau Protein, Rat (P.pastoris, His) is 751 a.a., with molecular weight of ~80.4 kDa.

HY-P73618

	Tau/0N3R Protein, Human (351a.a, His) MAPT; Mtapt; Tau; Microtubule-associated Protein Tau; PHF-Tau	Human	E. coli
	Tau/0N3R protein is encoded by the Tau/0N3R gene and undergoes regulated alternative splicing to produce different mRNA species. Its expression varies in the nervous system according to the maturation and type of neurons. Tau/0N3R Protein, Human (351a.a, His) is the recombinant human-derived Tau/0N3R protein, expressed by E. coli , with N-His labeled tag. The total length of Tau/0N3R Protein, Human (351a.a, His) is 351 a.a., with molecular weight of 40-50 kDa.

HY-P71102

	Tau-D/0N4R Protein, Human (133a.a, His) Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPT; MAPTL; MTBT1; Tau	Human	E. coli
	Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-D/0N4R Protein, Human (133a.a, His) is the recombinant human-derived Tau-D/0N4R protein, expressed by E. coli , with C-6*His labeled tag. The total length of Tau-D/0N4R Protein, Human (133a.a, His) is 133 a.a., with molecular weight of ~16.0 kDa.

HY-P700422

	Tau/MAPT Protein, Mouse (HEK293, His) MAPT; Tau; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated Protein Tau; microtubule-associated Protein Tau; PHF-Tau; paired helical filament-Tau; neurofibrillary tangle Protein; microtubule-associated Protein Tau, isoform 4; G Protein beta1/gamma2 subunit-interacting factor 1	Mouse	HEK293
	Microtubule-associated protein tau (MAPT) plays a pivotal role in promoting microtubule assembly and stability, indicating its potential contribution to neuronal polarity establishment. The C-terminus binds to axonal microtubules, while the N-terminus interacts with neural plasma membrane components, serving as a crucial linker protein between these structures. Tau's localization within the neuronal cell, particularly in the centrosome-defined domain, dictates axonal polarity. Short MAPT isoforms enhance cytoskeletal plasticity, while longer isoforms stabilize it. MAPT engages in diverse interactions with proteins like MARK1, MARK2, MARK3, MARK4, SQSTM1, PSMC2, FKBP4, CSNK1D, SGK1, EPM2A, PIN1, LRRK2, and LRP1, participating in processes from ubiquitination to dephosphorylation and endocytosis, underscoring its multifaceted role in cellular dynamics. Tau/MAPT Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Mouse (HEK293, His) is 732 a.a., with molecular weight of 78.9 kDa.

HY-P700424

	Tau/MAPT Protein, Rat (HEK293, His) MAPT; Tau; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated Protein Tau; microtubule-associated Protein Tau; PHF-Tau; paired helical filament-Tau; neurofibrillary tangle Protein; microtubule-associated Protein Tau, isoform 4; G Protein beta1/gamma2 subunit-interacting factor 1	Rat	HEK293
	Microtubule-associated protein tau (MAPT) critically promotes microtubule assembly and stability, influencing neuronal polarity by acting as a vital linker protein. Its dual role involves the C-terminus binding axonal microtubules and the N-terminus engaging neural plasma membrane components. Tau's cellular localization, especially near the centrosome, determines axonal polarity. Short tau isoforms offer cytoskeletal plasticity, while longer isoforms likely stabilize microtubules. MAPT engages with various proteins, including MARK1, MARK2, SQSTM1, LRP1, showcasing its multifaceted role in cellular processes. The interaction with LRP1, leading to endocytosis, highlights the intricate regulatory mechanisms governing tau's functional versatility. Tau/MAPT Protein, Rat (HEK293, His) is the recombinant rat-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Rat (HEK293, His) is 751 a.a., with molecular weight of 81.2 kDa.

HY-P700421

	Tau-F/MAPT Protein, Human (HEK293, His) MAPT; Tau; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated Protein Tau; microtubule-associated Protein Tau; PHF-Tau; paired helical filament-Tau; neurofibrillary tangle Protein; microtubule-associated Protein Tau, isoform 4; G Protein beta1/gamma2 subunit-interacting factor 1	Human	HEK293
	Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-F/MAPT Protein, Human (HEK293, His) is the recombinant human-derived Tau-F/MAPT protein, expressed by HEK293 , with N-10*His labeled tag. The total length of Tau-F/MAPT Protein, Human (HEK293, His) is 441 a.a., with molecular weight of 49.5 kDa.

HY-P700423

	Tau/MAPT Protein, Macaca mulatta (HEK293, His) MAPT; Tau; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated Protein Tau; microtubule-associated Protein Tau; PHF-Tau; paired helical filament-Tau; neurofibrillary tangle Protein; microtubule-associated Protein Tau, isoform 4; G Protein beta1/gamma2 subunit-interacting factor 1	Rhesus Macaque	HEK293
	Tau/MAPT Protein crucially promotes microtubule assembly and stability, essential for neuronal polarity. Structurally, its C-terminus binds axonal microtubules, and the N-terminus engages neural plasma membrane components, suggesting a role as a linker protein connecting microtubules to the plasma membrane. Tau's localization dictates axonal polarity, particularly near the centrosome. Short isoforms offer cytoskeletal plasticity, while longer isoforms stabilize microtubules. Tau interacts with proteins like MARK1, MARK2, SQSTM1, and LRP1, revealing its multifaceted role in cellular processes. Tau/MAPT Protein, Macaca mulatta (HEK293, His) is the recombinant Rhesus Macaque-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Macaca mulatta (HEK293, His) is 458 a.a., with molecular weight of 50.6 kDa.

HY-P70589

	Tau-F/MAPT Protein, Human DDPAC; FLJ31424; FTDP-17; G Protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated Protein Tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle Protein; MTBT2; Neurofibrillary tangle Protein; PHF-Tau; PPND; Tau; TauPaired helical filament-Tau	Human	E. coli
	Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-F/MAPT Protein, Human is the recombinant human-derived Tau-F/MAPT protein, expressed by E. coli , with tag free. The total length of Tau-F/MAPT Protein, Human is 441 a.a., with molecular weight of ~60.0 kDa.

HY-P71798

	*Interferon tau-1/IFNT1 Protein, Bovine (P.pastoris, His)* IFNT1; Interferon Tau-1; IFN-Tau-1; Antiluteolysin; Trophoblast antiluteolytic Protein; Trophoblast Protein 1; TP-1; Trophoblastin	Bovine	P. pastoris
	Interferon tau-1 (IFNT1) serves as an important paracrine hormone that initiates maternal recognition of pregnancy. After interacting with endometrial receptors, possibly type I interferon receptors, IFNT1 blocks estrogen receptor expression and prevents estrogen-induced upregulation of oxytocin receptor expression. Interferon tau-1/IFNT1 Protein, Bovine (P.pastoris, His) is the recombinant bovine-derived Interferon tau-1/IFNT1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of Interferon tau-1/IFNT1 Protein, Bovine (P.pastoris, His) is 172 a.a., with molecular weight of ~21.8 kDa.

HY-P75548

	*14-3-3 theta Protein, Human (GST)* 14-3-3 Protein theta; 14-3-3 Protein Tau; Protein HS1; YWHAQ	Human	E. coli
	14-3-3 theta protein, an adapter in diverse signaling pathways, recognizes phosphoserine or phosphothreonine motifs, modulating partner activity upon binding. It negatively regulates PDPK1 kinase activity, forms homodimers, and interacts with CDK16, phosphorylated RGS7, SSH1, phosphorylated CDKN1B, GAB2, phosphorylated PDPK1, and phosphorylated DAPK2. Additional interactions include PI4KB, TBC1D22A, TBC1D22B, SLITRK1, RIPOR2 isoform 2, INAVA, MARK2, MARK3, MARK4, and MEFV, highlighting its versatile role. 14-3-3 theta Protein, Human (GST) is the recombinant human-derived 14-3-3 theta protein, expressed by E. coli, with N-GST labeled tag. The total length of 14-3-3 theta Protein, Human (GST) is 245 a.a., with molecular weight of ~53 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P80613

CDK5 Antibody (YA796) Cdk 5; Cdk5; CDK5_HUMAN; Cell division Protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine Protein kinase PSSALRE; Serine/threonine-Protein kinase PSSALRE; Tau Protein kinas	WB, ICC/IF	Human, Mouse, Rat, Monkey
CDK5 Antibody (YA796) is a non-conjugated and Mouse origined monoclonal antibody about 33 kDa, targeting to CDK5 (2E8). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80539

AMPK alpha 1 Antibody PRKAA1; AMPK1; 5'-AMP-activated Protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-Protein kinase PRKAA1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
AMPK alpha 1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 64 kDa, targeting to AMPK alpha 1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80790

Phospho-AMPK alpha 1 (Ser496) Antibody PRKAA1; AMPK1; 5'-AMP-activated Protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-Protein kinase PRKAA1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
Phospho-AMPK alpha 1 (Ser496) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 64 kDa, targeting to Phospho-AMPK alpha 1 (Ser496). It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80909

Tau Antibody MAPT; MAPTL; MTBT1; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	WB	Human, Mouse, Rat
Tau Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 79 kDa, targeting to Tau. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80859

Phospho-Tau (Ser198) Antibody MAPT; MAPTL; MTBT1; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	WB, IP	Human
Phospho-Tau (Ser198) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 79 kDa, targeting to Phospho-Tau (Ser198). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80860

Phospho-Tau (Ser404) Antibody MAPT; MAPTL; MTBT1; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	WB	Human, Rat
Phospho-Tau (Ser404) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 79 kDa, targeting to Phospho-Tau (Ser404). It can be used for WB assays with tag free, in the background of Human, Rat.

HY-P80861

Phospho-Tau (Thr181) Antibody MAPT; MAPTL; MTBT1; Tau; Microtubule-associated Protein Tau; Neurofibrillary tangle Protein; Paired helical filament-Tau; PHF-Tau	WB, IP	Human
Phospho-Tau (Thr181) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 79 kDa, targeting to Phospho-Tau (Thr181). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P82210

14-3-3 theta Antibody (YA1955)

YWHAQ; 14-3-3 Protein theta; 14-3-3 Protein T-cell; 14-3-3 Protein Tau; Protein HS1
WB Human, Mouse, Rat

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